MaeN
Revision as of 11:34, 7 January 2014 by 134.76.70.252 (talk)
- Description: Na+/malate symporter
Gene name | maeN |
Synonyms | yufR |
Essential | no |
Product | Na+/malate symporter |
Function | malate uptake |
Gene expression levels in SubtiExpress: maeN | |
Metabolic function and regulation of this protein in SubtiPathways: maeN | |
MW, pI | 47 kDa, 8.411 |
Gene length, protein length | 1344 bp, 448 aa |
Immediate neighbours | nupQ, yufS |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
transporters/ other, utilization of specific carbon sources, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU31580
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: sodium:citrate (SCF) symporter family (according to Swiss-Prot) 2-hydroxycarboxylate transporter family
- Paralogous protein(s): CimH
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: O05256
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Sigma factor:
- Regulation: induced by malate (MalR)
- Regulatory mechanism: MalR: transcription activation
Biological materials
- Mutant:
- 1A642 (maeN::Tn917, erm) (available from the BGSC or in Jörg Stülke's lab)
- 1A642 ( maeN::erm), PubMed, available at BGSC
- GP1449 (erm), available in Stülke lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Iwona Sobczak, Juke S Lolkema
The 2-hydroxycarboxylate transporter family: physiology, structure, and mechanism.
Microbiol Mol Biol Rev: 2005, 69(4);665-95
[PubMed:16339740]
[WorldCat.org]
[DOI]
(P p)
Original publications