PlsY

• Description: acylphosphate:glycerol-phosphate acyltransferase
  
  

Gene name	plsY
Synonyms	yneS
Essential	yes PubMed
Product	acylphosphate:glycerol-phosphate acyltransferase
Function	biosynthesis of phospholipids
Gene expression levels in SubtiExpress: plsY
Interactions involving this protein in SubtInteract: PlsY
Metabolic function and regulation of this protein in SubtiPathways: Lipid synthesis
MW, pI	20 kDa, 10.408
Gene length, protein length	579 bp, 193 aa
Immediate neighbours	yneR, yneT
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

biosynthesis of lipids, essential genes, membrane proteins

The gene

Basic information

• Locus tag: BSU18070

Phenotypes of a mutant

essential PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Acyl-phosphate + sn-glycerol 3-phosphate = acyl-sn-glycerol 3-phosphate + phosphate (according to UniProt)

• Protein family: UPF0078 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • PlsY-PlsX PubMed

• Localization: cell membrane PubMed

Database entries

• Structure:

• UniProt: Q45064

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: plsY PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system: B. pertussis adenylate cyclase-based bacterial two hybrid system (BACTH), available in Matsumoto lab PubMed

• Antibody:

References

Reviews

Yasutaro Fujita, Hiroshi Matsuoka, Kazutake Hirooka
Regulation of fatty acid metabolism in bacteria.
Mol Microbiol: 2007, 66(4);829-39
[PubMed:17919287] [WorldCat.org] [DOI] (P p)

Stephen W White, Jie Zheng, Yong-Mei Zhang, Rock
The structural biology of type II fatty acid biosynthesis.
Annu Rev Biochem: 2005, 74;791-831
[PubMed:15952903] [WorldCat.org] [DOI] (P p)