Cofactors

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Contents

1 Nickel
2 Thiamine pyrophosphate
- 2.1 E1 subunits of ketoacid dehydrogenases/ acetoin dehydrogenase
3 Lipoic acid
- 3.1 E2 subunits of ketoacid dehydrogenases/ acetoin dehydrogenase
- 3.2 H protein of the glycine cleavage system
4 pyridoxyl phosphate
5 tetrahydrofalate

Nickel

UreA-UreB-UreC (urease), the nickel ion binds the active site in UreC

Thiamine pyrophosphate

E1 subunits of ketoacid dehydrogenases/ acetoin dehydrogenase

PdhA

Lipoic acid

E2 subunits of ketoacid dehydrogenases/ acetoin dehydrogenase

H protein of the glycine cleavage system

GcvH (also required for LipL-catalyzed octanoyl transfer from AcpA to the E2s)

pyridoxyl phosphate

GcvP

tetrahydrofalate

GcvT

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