SleB

• Description: spore cortex-lytic enzyme
  
  

Gene name	sleB
Synonyms	ypeA
Essential	no
Product	spore cortex-lytic enzyme
Function	degration of the spore cortex, germination
Gene expression levels in SubtiExpress: sleB
MW, pI	33 kDa, 9.506
Gene length, protein length	915 bp, 305 aa
Immediate neighbours	ypeB, prsW
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

germination, membrane proteins

This gene is a member of the following regulons

SigG regulon

The gene

Basic information

• Locus tag: BSU22930

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: sleB family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:
  • contains a signal peptide PubMed

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • outer surface of the inner spore membrane PubMed

Database entries

• Structure:

• UniProt: P50739

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: sleB-ypeB PubMed

• Expression browser: sleB PubMed

• Sigma factor: SigG PubMed

• Regulation:
  • expressed late during sporulation in the forespore (SigG) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:
  • 1G21 ( sleB::spec), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: