YflL

• Description: acylphosphatase
  
  

Gene name	yflL
Synonyms
Essential	no
Product	acylphosphatase
Function	unknown
Gene expression levels in SubtiExpress: yflL
MW, pI	10 kDa, 8.666
Gene length, protein length	273 bp, 91 aa
Immediate neighbours	nos, yflK
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

poorly characterized/ putative enzymes

The gene

Basic information

• Locus tag: BSU07640

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: An acylphosphate + H₂O = a carboxylate + phosphate (according to Swiss-Prot)

• Protein family: acylphosphatase-like domain (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 3BR8, 2FHM PubMed

• UniProt: O35031

• KEGG entry: [3]

• E.C. number: 3.6.1.7

Expression and regulation

• Operon: yflL (according to DBTBS)

• Expression browser: yflL PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:
  • yflL transcription occurs in antisense orientation as compared to the surrounding nos-yflK operon

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Jicheng Hu, Dan Li, Xiao-Dong Su, Changwen Jin, Bin Xia
Solution structure and conformational heterogeneity of acylphosphatase from Bacillus subtilis.
FEBS Lett: 2010, 584(13);2852-6
[PubMed:20447399] [WorldCat.org] [DOI] (I p)