ScoA

• Description: probable succinyl CoA:3-oxoacid CoA-transferase (subunit A)
  
  

Gene name	scoA
Synonyms	yxjD
Essential	no
Product	probable succinyl CoA:3-oxoacid CoA-transferase (subunit A)
Function	lipid metabolism
Gene expression levels in SubtiExpress: scoA
MW, pI	25 kDa, 6.613
Gene length, protein length	714 bp, 238 aa
Immediate neighbours	scoB, yxjC
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

utilization of lipids, sporulation proteins

This gene is a member of the following regulons

CcpA regulon, SigE regulon

The gene

Basic information

• Locus tag: BSU38990

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Succinyl-CoA + a 3-oxo acid = succinate + a 3-oxoacyl-CoA (according to Swiss-Prot)

• Protein family: 3-oxoacid CoA-transferase subunit A family (according to Swiss-Prot)

• Paralogous protein(s): YodS

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 3CDK

• UniProt: P42315

• KEGG entry: [3]

• E.C. number: 2.8.3.5

Expression and regulation

• Operon: yxjC-scoA-scoB-yxjF PubMed

• Expression browser: scoA PubMed

• Sigma factor: SigE PubMed

• Regulation:
  • repressed by glucose (CcpA) PubMed
  • expressed early during sporulation in the mother cell (SigE) PubMed

• Regulatory mechanism:
  • CcpA: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: