AdhB

• Description: forespore-specific protein, similar to alcohol dehydrogenase
  
  

Gene name	adhB
Synonyms
Essential	no
Product	unknown
Function	unknown
Gene expression levels in SubtiExpress: adhB
MW, pI	41 kDa, 5.659
Gene length, protein length	1134 bp, 378 aa
Immediate neighbours	yraF, yraE
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

sporulation proteins, poorly characterized/ putative enzymes

This gene is a member of the following regulons

SigG regulon

The gene

Basic information

• Locus tag: BSU26970

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: Class-III subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: spore wall (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O06012

• KEGG entry: [3]

• E.C. number:

Additional information

The gene is annotated in KEGG as alcohol dehydrogenase EC 1.1.1.284. It is annotated in Swiss-Prot as “NAD alcohol dehydrogenase”. It is marked as “alcohol dehydrogenase” in MetaCyc. No literature/experimental evidence supporting the annotation is available. PubMed

Expression and regulation

• Operon: yraG-yraF-adhB-yraE-yraD PubMed

• Sigma factor: SigG PubMed

• Regulation:
  • expressed during sporulation in the forespore (SigG) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Stephanie T Wang, Barbara Setlow, Erin M Conlon, Jessica L Lyon, Daisuke Imamura, Tsutomu Sato, Peter Setlow, Richard Losick, Patrick Eichenberger
The forespore line of gene expression in Bacillus subtilis.
J Mol Biol: 2006, 358(1);16-37
[PubMed:16497325] [WorldCat.org] [DOI] (P p)