FtsX

• Description: ABC transporter (membrane protein) (FtsE-FtsX), required for proper activation of Spo0A and initiation of sporulation
  
  

Gene name	ftsX
Synonyms
Essential	no
Product	ABC transporter (membrane protein)
Function	initiation of sporulation
Gene expression levels in SubtiExpress: ftsX
Interactions involving this protein in SubtInteract: FtsX
MW, pI	32 kDa, 10.016
Gene length, protein length	888 bp, 296 aa
Immediate neighbours	ctpB, ftsE
Sequences	Protein DNA Advanced_DNA
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, phosphorelay, membrane proteins

This gene is a member of the following regulons

Spo0A regulon

The gene

Basic information

• Locus tag: BSU35250

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: FtsX subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • FtsE-FtsX PubMed
  • FloT-FtsX PubMed

• Localization: cell membrane (according to Swiss-Prot), membrane associated PubMed

Database entries

• Structure:

• UniProt: O34876

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: ftsE-ftsX (according to DBTBS)

• Expression browser: ftsX PubMed

• Sigma factor:

• Regulation:
  • repressed under conditions that trigger sporulation (Spo0A) PubMed

• Regulatory mechanism:
  • Spo0A: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: