CsgA

• Description: required for the ability of the germinating spore to resume vegetative growth
  
  

Gene name	csgA
Synonyms
Essential	no
Product	unknown
Function	spore germination
Gene expression levels in SubtiExpress: csgA
MW, pI	9 kDa, 4.694
Gene length, protein length	246 bp, 82 aa
Immediate neighbours	ybxG, ybxH
Sequences	Protein DNA Advanced_DNA
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

germination

This gene is a member of the following regulons

SigG regulon, SpoVT regulon

The gene

Basic information

• Locus tag: BSU02070

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P54379

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: csgA-ybxH PubMed

• Expression browser: csgA PubMed

• Sigma factor: SigG PubMed

• Regulation:
  • expressed during sporulation in the forespore (SpoVT) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190] [WorldCat.org] [DOI] (P p)

M Shcheptov, G Chyu, I Bagyan, S Cutting
Characterization of csgA, a new member of the forespore-expressed sigmaG-regulon from Bacillus subtilis.
Gene: 1997, 184(1);133-40
[PubMed:9016963] [WorldCat.org] [DOI] (P p)