SpsJ

• Description: dTDP -glucose-4,6-dehydratase, spore coat polysaccharide synthesis
  
  

Gene name	spsJ
Synonyms	ipa-72d
Essential	no
Product	dTDP -glucose-4,6-dehydratase
Function	rhamnose biosynthesis, spore coat polysaccharide synthesis
Gene expression levels in SubtiExpress: spsJ
MW, pI	35 kDa, 6.286
Gene length, protein length	945 bp, 315 aa
Immediate neighbours	spsK, spsI
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

miscellaneous metabolic pathways, sporulation proteins

This gene is a member of the following regulons

SigE regulon, SigK regulon

The gene

Basic information

• Locus tag: BSU37830

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:
  • dTDP-glucose --> dTDP-4-dehydro-6-deoxyglucose PubMed

• Protein family: sugar epimerase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P39630

• KEGG entry: [3]

• E.C. number: 4.2.1.46

Expression and regulation

• Operon: spsA-spsB-spsC-spsD-spsF-spsG-spsI-spsJ-spsK-spsL PubMed

• Expression browser: spsJ PubMed

• Sigma factor: SigK PubMed

• Regulation:
  • expressed late during sporulation in the mother cell (SigK) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: