YhcH

• Description: similar to ABC transporter (ATP-binding protein)
  
  

Gene name	yhcH
Synonyms
Essential	no
Product	ABC transporter (ATP-binding protein)
Function	unknown
Gene expression levels in SubtiExpress: yhcH
Interactions involving this protein in SubtInteract: YhcH
MW, pI	34 kDa, 6.37
Gene length, protein length	915 bp, 305 aa
Immediate neighbours	yhcG, yhcI
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, membrane proteins

The gene

Basic information

• Locus tag: BSU09080

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ABC transporter domain (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • YhcH-YhcI PubMed

• Localization: membrane associated (via YhcI) PubMed

Database entries

• Structure:

• UniProt: P54592

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: yhbI-yhbJ-yhcA-yhcB-yhcC-yhcD-yhcE-yhcF-yhcG-yhcH-yhcI PubMed

• Expression browser: yhcH PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:
  • the mRNA is substantially stabilized upon depletion of RNase Y (the half-life of the mRNA increases from 4 to 41 min) PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Lehnik-Habrink M, Schaffer M, Mäder U, Diethmaier C, Herzberg C, Stülke J  
RNA processing in Bacillus subtilis: identification of targets of the essential RNase Y. 
Mol Microbiol. 2011 81(6): 1459-1473. 
PubMed:21815947

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)