BdhA

• Description: acetoine/ butanediol dehydrogenase
  
  

Gene name	bdhA
Synonyms	ydjL
Essential	no
Product	acetoine/ butanediol dehydrogenase
Function	overflow metabolism, fermentation
MW, pI	37 kDa, 4.805
Gene length, protein length	1038 bp, 346 aa
Immediate neighbours	iolT, ydjM
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

carbon core metabolism

This gene is a member of the following regulons

AbrB regulon

The gene

Basic information

• Locus tag: BSU06240

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: formation of butanediol from acetoin PubMed

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O34788

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: bdhA (according to DBTBS)

• Expression browser: bdhA PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:
  • AbrB: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed

Ranjita Biswas, Masaru Yamaoka, Hideki Nakayama, Takashi Kondo, Ken-ichi Yoshida, Virendra S Bisaria, Akihiko Kondo
Enhanced production of 2,3-butanediol by engineered Bacillus subtilis.
Appl Microbiol Biotechnol: 2012, 94(3);651-8
[PubMed:22361854] [WorldCat.org] [DOI] (I p)

Wayne L Nicholson
The Bacillus subtilis ydjL (bdhA) gene encodes acetoin reductase/2,3-butanediol dehydrogenase.
Appl Environ Microbiol: 2008, 74(22);6832-8
[PubMed:18820069] [WorldCat.org] [DOI] (I p)