PanC

• Description: pantothenate synthase
  
  

Gene name	panC
Synonyms
Essential	no
Product	pantothenate synthase
Function	biosynthesis of coenzyme A
Metabolic function and regulation of this protein in SubtiPathways: Coenzyme A
MW, pI	31 kDa, 4.626
Gene length, protein length	858 bp, 286 aa
Immediate neighbours	panD, panB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

biosynthesis of cofactors

The gene

Basic information

• Locus tag: BSU22420

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: ATP + (R)-pantoate + beta-alanine = AMP + diphosphate + (R)-pantothenate (according to Swiss-Prot)

• Protein family: short-chain dehydrogenases/reductases (SDR) family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cytoplasm (according to Swiss-Prot)

Database entries

• Structure: 2EJC (from Thermotoga maritima, 50% identity, 66% similarity)

• UniProt: P52998

• KEGG entry: [2]

• E.C. number: 6.3.2.1

Expression and regulation

• Operon:

• Expression browser: panC PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: