YngG

• Description: 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) lyase
  
  

Gene name	yngG
Synonyms
Essential	no
Product	3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) lyase
Function	mother cell metabolism, leucine utilization
MW, pI	32 kDa, 5.753
Gene length, protein length	897 bp, 299 aa
Immediate neighbours	yngF, yngH
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

utilization of amino acids, sporulation proteins

This gene is a member of the following regulons

SigE regulon

The gene

Basic information

• Locus tag: BSU18230

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: (S)-3-hydroxy-3-methylglutaryl-CoA = acetyl-CoA + acetoacetate PubMed

• Protein family: HMG-CoA lyase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 1YDO

• UniProt: O34873

• KEGG entry: [3]

• E.C. number: 4.1.3.4

Expression and regulation

• Operon: yngJ-yngI-yngH-yngHB-yngG-yngF-yngE PubMed

• Sigma factor: SigE PubMed

• Regulation:
  • expressed during sporulation in the mother cell (SigE) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: