YngG

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  • Description: 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) lyase

Gene name yngG
Synonyms
Essential no
Product 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) lyase
Function mother cell metabolism, leucine utilization
MW, pI 32 kDa, 5.753
Gene length, protein length 897 bp, 299 aa
Immediate neighbours yngF, yngH
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YngG context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

utilization of amino acids, sporulation proteins

This gene is a member of the following regulons

SigE regulon

The gene

Basic information

  • Locus tag: BSU18230

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: (S)-3-hydroxy-3-methylglutaryl-CoA = acetyl-CoA + acetoacetate PubMed
  • Protein family: HMG-CoA lyase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • expressed during sporulation in the mother cell (SigE) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References