RNases

RNases are involved in the processing and degradation of the different classes of mRNAs, tRNAs, rRNAs and small RNAs

Parent categories	3. Information processing 3.2. RNA synthesis and degradation
Neighbouring categories	3.2.1. Transcription 3.2.2. RNA chaperones 3.2.3. DEAD-box RNA helicases 3.2.4. RNases
Related categories	RNA degradosome
Overview on the categories (Excel file) All genes and their categories (Excel file)

Exoribonucleases

• RNase J1: 5'-3' activity, does also have endonuclease activity

• RNase PH: 3'-5' activity
• YhaM: 3'-5' activity
• RNase R: 3'-5' activity
• polynucleotide phosphorylase: 3'-5' activity

• nano-RNase A: degrades oligonucleotides
• nano-RNase B: degrades oligonucleotides

Endoribonucleases

• RNase J1: ssRNA endonuclease, does also have exonuclease activity
• RNase J2: ssRNA endonuclease, may also have exonuclease activity

• RNase Y: ssRNA endonuclease
• RNase P: ssRNA endonuclease
• RNase Z: ssRNA endonuclease

• RNase Endo A

• RNase HII: cleaves RNA in RNA-DNA hybrids
• RNase HIII: cleaves RNA in RNA-DNA hybrids

• RNase Bsn: extracellular RNase

• RNase III: dsRNA endonuclease
• mini-III: dsRNA endonuclease
• RNase M5: dsRNA endonuclease

Labs working on RNases

• David Bechhofer
• Ciaran Condon
• Harald Putzer
• Jörg Stülke

Key original publications

G Hambraeus, C von Wachenfeldt, L Hederstedt
Genome-wide survey of mRNA half-lives in Bacillus subtilis identifies extremely stable mRNAs.
Mol Genet Genomics: 2003, 269(5);706-14
[PubMed:12884008] [WorldCat.org] [DOI] (P p)

Reviews on RNases in Bacillus subtilis

Additional reviews: PubMed