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Welcome to SubtiWiki! - Bacillus subtilis annotation the "wiki" way!
Contact: General Microbiology, University of Göttingen, send mail
Upcoming events:
- April 16 - 19, 2012: The 5th European Spore Conference will take place in London, UK. contact, conference website
- April 24 - 25, 2012: The BACELL meeting 2012 will be organized by Kevin Devine in Dublin, Ireland. contact
New: Subtiwiki is now on Facebook - please give it a +1!
New: Paper of the month: July 2011
- Domínguez-Escobar et al. from Rut Carballido-Lopez' lab and Garner et al. report that movement of actin-like filaments is driven by the peptidoglycan elongation machinery. Both papers suggest that the MreB-like filaments serve to restrict the mobility of the peptidoglycan synthesizing machinery
- Relevant SubtiWiki pages: Rut Carballido-Lopez, David Rudner, MreB, MreBH, Mbl, MreC, MreD, PbpA, RodA, RodZ, penicillin-binding proteins, cell shape, cell wall synthesis, cell wall biosynthetic complex
Ethan C Garner, Remi Bernard, Wenqin Wang, Xiaowei Zhuang, David Z Rudner, Tim Mitchison
Coupled, circumferential motions of the cell wall synthesis machinery and MreB filaments in B. subtilis.
Science: 2011, 333(6039);222-5
[PubMed:21636745]
[WorldCat.org]
[DOI]
(I p)
Julia Domínguez-Escobar, Arnaud Chastanet, Alvaro H Crevenna, Vincent Fromion, Roland Wedlich-Söldner, Rut Carballido-López
Processive movement of MreB-associated cell wall biosynthetic complexes in bacteria.
Science: 2011, 333(6039);225-8
[PubMed:21636744]
[WorldCat.org]
[DOI]
(I p)
- A comment on these papers:
Andrew Jermy
Bacterial physiology: MreB takes a back seat.
Nat Rev Microbiol: 2011, 9(8);560-1
[PubMed:21725336]
[WorldCat.org]
[DOI]
(I e)
New procedure for account creation:
- Due to massive spam attacks, we had to change our policy for the creation of accounts. If you want to create an account, just send me a mail. We will create the account for you as quickly as possible, then you can change your password. This does not affect existing accounts, which remain active.
- Please remember that all members of the Bacillus community are invited to create accounts and to contribute to SubtiWiki!
News in SubtiWiki:
- June 2011: updated Excel files that map all genes to categories and regulons as well as the general updated identity mapping of all genes were uploaded.
- April 2011: SubtInteract, a presentation of protein-protein interactions in B. subtilis, is online!
- December 2010: SubtiCellPublisher allows the conversion of CellDesigner diagrams to navigatable presentations in the style of SubtiPathways
- December 2010: all genes are linked to regulons, and the pages of the regulons provide an overview on all genes that are members of this specific regulon.
- December 2010: all genes/proteins are linked to categories, and the pages of the categories provide an overview on all genes/proteins that are members of this specific category.
- August 2010: several new pathway maps including Utilization of other nitrogen sources, Biotin synthesis, Murein recycling, and Protein secretion were uploaded to SubtiPathways
- July 2010: A manually curated functional classification of Bacillus genes can be downloaded here.
- March 2010: novel plasmids for the creation of strains expressing proteins with a C-terminal triple FLAG-tag (for simple immunological analysis of the proteins, pGP1087 and pGP1331)
Publications describing SubtiWiki and SubtiPathways:
Lope A Flórez, Sebastian F Roppel, Arne G Schmeisky, Christoph R Lammers, Jörg Stülke
A community-curated consensual annotation that is continuously updated: the Bacillus subtilis centred wiki SubtiWiki.
Database (Oxford): 2009, 2009;bap012
[PubMed:20157485]
[WorldCat.org]
[DOI]
(I p)
Christoph R Lammers, Lope A Flórez, Arne G Schmeisky, Sebastian F Roppel, Ulrike Mäder, Leendert Hamoen, Jörg Stülke
Connecting parts with processes: SubtiWiki and SubtiPathways integrate gene and pathway annotation for Bacillus subtilis.
Microbiology (Reading): 2010, 156(Pt 3);849-859
[PubMed:19959575]
[WorldCat.org]
[DOI]
(I p)
