ArtR

• Description: high affinity arginine ABC transporter (ATP-binding protein)
  
  

Gene name	artR
Synonyms	yqiZ
Essential	no
Product	high affinity arginine ABC transporter (ATP-binding protein)
Function	arginine uptake
Metabolic function and regulation of this protein in SubtiPathways: Ammonium/ glutamate
MW, pI	26 kDa, 9.131
Gene length, protein length	720 bp, 240 aa
Immediate neighbours	yqjA, artQ
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

ABC transporters, biosynthesis/ acquisition of amino acids, membrane proteins

The gene

Basic information

• Locus tag: BSU23960

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ABC transporter family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: ArtR-ArtQ-ArtP PubMed

• Localization: attached to the membrane via ArtQ PubMed

Database entries

• Structure: 2Q0H (in complex with ADP-Mg2+, Geobacillus stearothermophilus, 63% identity)

• Swiss prot entry: P54537

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: artP-artQ-artR PubMed

• Sigma factor:

• Regulation:
  • repressed by casamino acids PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Ulrike Mäder, Georg Homuth, Christian Scharf, Knut Büttner, Rüdiger Bode, Michael Hecker
Transcriptome and proteome analysis of Bacillus subtilis gene expression modulated by amino acid availability.
J Bacteriol: 2002, 184(15);4288-95
[PubMed:12107147] [WorldCat.org] [DOI] (P p)

A Sekowska, S Robin, J J Daudin, A Hénaut, A Danchin
Extracting biological information from DNA arrays: an unexpected link between arginine and methionine metabolism in Bacillus subtilis.
Genome Biol: 2001, 2(6);RESEARCH0019
[PubMed:11423008] [WorldCat.org] [DOI] (I p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)