arsR

arsR
168

transcriptional regulator of the ArsR family, arsenic resistance operon repressor

Locus
BSU_25810
Molecular weight
12.15 kDa
Isoelectric point
4.88
Protein length
105 aaSequenceBlast
Gene length
318 bpSequenceBlast
Function
regulation of As (III) efflux
Product
transcription repressor (ArsR family)
Essential
no
Synonyms
arsR, yqcJ
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0640 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,657,317 → 2,657,634
The protein
Protein family
ArsR family
Domains
HTH arsR-type domain (aa 4-99) (according to UniProt)
Structure
1U2W (PDB) (CadC from Staphylococcus aureus, 36% identity) PubMed
P45949 (AlphaFold)
Expression and Regulation
Operons
Genes
arsR-yqcK-arsB-arsC
Description
PubMed
Regulation
expressed early during sporulation in the forespore (SigF) PubMed
Regulatory mechanism
ArsR: repression, PubMed, in arsR regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
SigF: sigma factor, PubMed, in sigF regulon
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arsR→arsC

2025-04-05 06:52:38

ghost

83

7d91428def687f36edd853c2144ba36ad881df9d

CB498A4267C57A4A9612EB861EB870A4C106D7B1

Biological materials
Mutant
BKE25810 (ΔarsR::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTCATATCGCCTTCTTTA,  downstream forward: _UP4_TAAAAAAATTTTTTAGGTAT
BKK25810 (ΔarsR::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTCATATCGCCTTCTTTA,  downstream forward: _UP4_TAAAAAAATTTTTTAGGTAT
References
Reviews
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Original Publications
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B3D88B9C89154B77D77FB833CA16FD4F4E29FE96

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Time of last update: 2025-04-09 08:23:55

Author of last update: Jstuelk