yerI

yerI
168

amicoumacin kinase

Locus
BSU_06640
Molecular weight
39.18 kDa
Isoelectric point
4.87
Protein length
336 aaSequenceBlast
Gene length
1011 bpSequenceBlast
Function
resistance to amicoumacin
Product
amicoumacin kinase
Essential
no
E.C.
null
Synonyms
yerI
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2334 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
724,987  725,997
The protein
Catalyzed reaction/ biological activity
Phosphorylates the antibiotic amicoumacin A (Ami), leading to its inactivation PubMed
Protein family
pseudomonas-type thrB family (single member, according to UniProt)
Structure
6EF6 (PDB) (from Mycobacterium smegmatis, corresponds to aa 17 ... 286, 25% identity) PubMed
O34640 (AlphaFold)
Expression and Regulation
Operons
Genes
yerI
Description
PubMed
Regulatory mechanism
AbrB: repression, PubMed, in abrB regulon
Open in new tab

yerI

2025-03-07 03:19:18

Bzhu

58

a56668cf0046c0880007d3ea7566d21e0aa1c213

FFAD73287358DCF651625682C4826AFB98332AEA

Biological materials
Mutant
MGNA-A927 (yerI::erm), available at the NBRP B. subtilis, Japan
BKE06640 (yerI::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCCTTTCATTGCTATAGA,  downstream forward: _UP4_TAGATAGAAAAAGCCAATGG
BKK06640 (yerI::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCCTTTCATTGCTATAGA,  downstream forward: _UP4_TAGATAGAAAAAGCCAATGG
References
Loading

2AF5F4142F3459A651FCB4057D6B92B9C1D76C6D

Page visits: 1923

Time of last update: 2025-03-27 05:22:42

Author of last update: Jstuelk