CotZ

• Description: spore coat protein (insoluble fraction), necessary for the assembly of the spore crust, the outermost layer of the spore coat
  
  

Gene name	cotZ
Synonyms
Essential	no
Product	spore coat protein (insoluble fraction)
Function	spore coat assembly
MW, pI	16 kDa, 5.102
Gene length, protein length	444 bp, 148 aa
Immediate neighbours	cotO, cotY
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU11740

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: CotY-CotZ PubMed

• Localization: outermost layer of the spore coat, more abundant at the mother cell-proximal pole of the forespore PubMed

Database entries

• Structure:

• UniProt: Q08312

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: cotY-cotZ PubMed

• Sigma factor: SigK PubMed

• Regulation:
  • expressed late during sporulation in the mother cell (SigK) PubMed

• Regulatory mechanism:
  • GerE: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: