ValS
-  Description: valyl-tRNA synthetase 
| Gene name | valS | 
| Synonyms | |
| Essential | yes PubMed | 
| Product | valyl-tRNA synthetase | 
| Function | translation | 
| MW, pI | 101 kDa, 4.868 | 
| Gene length, protein length | 2640 bp, 880 aa | 
| Immediate neighbours | folC, ysxE | 
| Get the DNA and protein sequences (Barbe et al., 2009) | |
| Genetic context    This image was kindly provided by SubtiList | |
Contents
The gene
Basic information
- Locus tag: BSU28090
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val) (according to Swiss-Prot)
- Protein family: ValS type 1 subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- Swiss prot entry: Q05873
- KEGG entry: [3]
- E.C. number: 6.1.1.9
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Ana Gutiérrez-Preciado, Tina M Henkin, Frank J Grundy, Charles Yanofsky, Enrique Merino  
Biochemical features and functional implications of the RNA-based T-box regulatory mechanism. 
Microbiol Mol Biol Rev: 2009, 73(1);36-61 
[PubMed:19258532]
  [WorldCat.org]
 [DOI]
 (I p)
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed

