DacF
- Description: penicillin-binding protein I, D-alanyl-D-alanine carboxypeptidase
| Gene name | dacF |
| Synonyms | |
| Essential | no |
| Product | penicillin-binding protein I, D-alanyl-D-alanine carboxypeptidase |
| Function | carboxypeptidase |
| Metabolic function and regulation of this protein in SubtiPathways: Stress | |
| MW, pI | 43 kDa, 9.912 |
| Gene length, protein length | 1167 bp, 389 aa |
| Immediate neighbours | spoIIAA, punA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU23480
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Preferential cleavage: (Ac)(2)-L-Lys-D-Ala-|-D-Ala (according to Swiss-Prot)
- Protein family: peptidase S11 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- Swiss prot entry: P38422
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation: repressed by casamino acids PubMed , expressed during sporulation in the prespore Link to a summary
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Ulrike Mäder, Georg Homuth, Christian Scharf, Knut Büttner, Rüdiger Bode, Michael Hecker
Transcriptome and proteome analysis of Bacillus subtilis gene expression modulated by amino acid availability.
J Bacteriol: 2002, 184(15);4288-95
[PubMed:12107147]
[WorldCat.org]
[DOI]
(P p)
