L-box
The L-box is a riboswitch that binds lysine and controls gene expression by a termination/ antitermination mechanism. Upon binding of lysine, the L-box adopts a terminator structure thtus preventing expression of lysC. In the absence of lysine, the L-box has an antiterminator structure that allows lysC expression and thus lysine biosynthesis.
Gene controlled by a L-box mechanism
Reference
Frank J Grundy, Susan C Lehman, Tina M Henkin
The L box regulon: lysine sensing by leader RNAs of bacterial lysine biosynthesis genes.
Proc Natl Acad Sci U S A: 2003, 100(21);12057-62
[PubMed:14523230]
[WorldCat.org]
[DOI]
(P p)
