SigF
- Description: RNA polymerase forespore-specific (early) sigma factor SigF
| Gene name | sigF |
| Synonyms | spoIIAC |
| Essential | no |
| Product | RNA polymerase forespore-specific (early) sigma factor SigF |
| Function | transcription of sporulation genes (late mother cell) |
| MW, pI | 29 kDa, 5.078 |
| Gene length, protein length | 765 bp, 255 aa |
| Immediate neighbours | spoVAA, spoIIAB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag:
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: sigma-70 factor family (according to Swiss-Prot)
- Paralogous protein(s):
Genes controlled by SigF
dacF-spoIIAA-spoIIAB-sigF, sigG, pbpF, yphA-seaA
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure: 1L0O (complex with SpoIIAB, Geobacillus stearothermophilus)
- Swiss prot entry: P07860
- KEGG entry: BSU23450
- E.C. number:
Additional information
Expression and regulation
- Sigma factor: dacF: SigF, SigG
- Regulation: repressed by casamino acids PubMed , dacF: expressed during sporulation, spoIIAA: expressed early during sporulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
- Charles Moran, Emory University, NC, USA homepage
