MgsR
- Description: transcriptional regulator of a subset of the SigB general stress regulon
| Gene name | mgsR |
| Synonyms | yqgZ |
| Essential | no |
| Product | transcriptional regulator |
| Function | controls a subset of general stress genes |
| MW, pI | 14 kDa, 9.28 |
| Gene length, protein length | 378 bp, 126 aa |
| Immediate neighbours | trnSL-Gln1, yqgY |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: exerts a positive or negative effect on the expression of 53 or 18 stress genes, respectively PubMed
- Protein family: arsC family (according to Swiss-Prot) Arsenate Reductase (ArsC) family, Spx subfamily
- Paralogous protein(s): Spx
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- Swiss prot entry: P54503
- KEGG entry: BSU24770
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation: repressed by casamino acids PubMed , induced by stress (SigB) PubMed, expressed under stress conditions PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
- Mäder et al. (2002) Transcriptome and Proteome Analysis of Bacillus subtilis Gene Expression Modulated by Amino Acid Availability. J. Bacteriol 184: 1844288-4295 PubMed
- Höper et al. (2005) Comprehensive Characterization of the Contribution of Individual SigB-Dependent General Stress Genes to Stress Resistance of Bacillus subtilis. J. Bact. 187: 2810-2826 PubMed
- Reder et al. (2008) The Spx paralogue MgsR (YqgZ) controls a subregulon within the general stress response of Bacillus subtilis. Mol. Microbiol. 69: 1104-1120. PubMed
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed
