YybP

• Description: unknown
  
  

Gene name	yybP
Synonyms
Essential	no
Product	unknown
Function	unknown
Gene expression levels in SubtiExpress: yybP
MW, pI	15 kDa, 4.24
Gene length, protein length	444 bp, 148 aa
Immediate neighbours	ppaC, yybO
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

membrane proteins, sporulation proteins

The gene

Basic information

• Locus tag: BSU40560

Database entries

• BsubCyc: BSU40560

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane (according to Swiss-Prot)

Database entries

• BsubCyc: BSU40560

• Structure:

• UniProt: P37488

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yybP PubMed

• Expression browser: yybP PubMed

• Sigma factor:

• Regulation:
  • induced in the presence of Mn²⁺ (yybP-ykoY motif) PubMed

• Regulatory mechanism:
  • yybP-ykoY motif, riboswitch, antitermination in the presence of the ligand Mn²⁺ PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Ian R Price, Ahmed Gaballa, Fang Ding, John D Helmann, Ailong Ke
Mn(2+)-sensing mechanisms of yybP-ykoY orphan riboswitches.
Mol Cell: 2015, 57(6);1110-1123
[PubMed:25794619] [WorldCat.org] [DOI] (I p)

Michael Dambach, Melissa Sandoval, Taylor B Updegrove, Vivek Anantharaman, L Aravind, Lauren S Waters, Gisela Storz
The ubiquitous yybP-ykoY riboswitch is a manganese-responsive regulatory element.
Mol Cell: 2015, 57(6);1099-1109
[PubMed:25794618] [WorldCat.org] [DOI] (I p)

Jeffrey E Barrick, Keith A Corbino, Wade C Winkler, Ali Nahvi, Maumita Mandal, Jennifer Collins, Mark Lee, Adam Roth, Narasimhan Sudarsan, Inbal Jona, J Kenneth Wickiser, Ronald R Breaker
New RNA motifs suggest an expanded scope for riboswitches in bacterial genetic control.
Proc Natl Acad Sci U S A: 2004, 101(17);6421-6
[PubMed:15096624] [WorldCat.org] [DOI] (P p)