MoaD

• Description: molybdopterin synthase (small subunit)
  
  

Gene name	moaD
Synonyms
Essential	no
Product	molybdopterin synthase (small subunit)
Function	nitrate respiration
Gene expression levels in SubtiExpress: moaD
Interactions involving this protein in SubtInteract: MoaD
MW, pI	7 kDa, 3.829
Gene length, protein length	231 bp, 77 aa
Immediate neighbours	moaE, yknU
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

biosynthesis of cofactors

The gene

Basic information

• Locus tag: BSU14310

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactors:

• Effectors of protein activity:

• Interactions:
  • MoaD-MoaE (as deduced from E. coli, PubMed)

• Localization:

Database entries

• Structure:
  • 1NVI (the MoaD-MoaE complex from E. coli) PubMed

• UniProt: O31706

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: mobA-moeB-moeA-mobB-moaE-moaD PubMed

• Expression browser: moaD PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

Ralf R Mendel
The molybdenum cofactor.
J Biol Chem: 2013, 288(19);13165-72
[PubMed:23539623] [WorldCat.org] [DOI] (I p)

Tadhg P Begley, Steven E Ealick, Fred W McLafferty
Thiamin biosynthesis: still yielding fascinating biological chemistry.
Biochem Soc Trans: 2012, 40(3);555-60
[PubMed:22616866] [WorldCat.org] [DOI] (I p)