CotB

• Description: spore coat protein (outer)
  
  

Gene name	cotB
Synonyms
Essential	no
Product	spore coat protein (outer)
Function	resistance of the spore
Gene expression levels in SubtiExpress: cotB
Interactions involving this protein in SubtInteract: CotB
MW, pI	42 kDa, 9.831
Gene length, protein length	1140 bp, 380 aa
Immediate neighbours	ywrJ, cotH
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

sporulation proteins

This gene is a member of the following regulons

GerE regulon, GerR regulon, SigK regulon, SigE regulon

The gene

Basic information

• Locus tag: BSU36050

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • CotB-CotG PubMed

• Localization:
  • outer spore coat, at the middle of the spore as a ring- or spiral-like structure, localization depends on CotE PubMed

Database entries

• Structure:

• UniProt: P07789

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: cotB PubMed

• Sigma factor: SigE PubMed, SigK PubMed,

• Regulation:
  • expressed late during sporulation in the mother cell (SigE, SigK, GerE, GerR) PubMed

• Regulatory mechanism:
  • GerE: transcription activation PubMed
  • GerR: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:
  • 1S102 ( cotB::cat), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: