MalL

• Description: alpha-glucosidase
  
  

Gene name	malL
Synonyms	yvdL
Essential	no
Product	alpha-glucosidase
Function	starch and maltodextrin utilization
Gene expression levels in SubtiExpress: malL
Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism, Sugar catabolism
MW, pI	65 kDa, 4.98
Gene length, protein length	1683 bp, 561 aa
Immediate neighbours	pgcM, yvdK
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

utilization of specific carbon sources

The gene

Basic information

• Locus tag: BSU34560

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Hydrolysis of (1->6)-alpha-D-glucosidic linkages in some oligosaccharides produced from starch and glycogen by alpha-amylase, and in isomaltose (according to Swiss-Prot)

• Protein family: glycosyl hydrolase 13 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• Structure: 1UOK (from Bacillus cereus, 57% identity, 74% similarity) PubMed

• UniProt: O06994

• KEGG entry: [2]

• E.C. number: 3.2.1.10

Expression and regulation

• Operon: yvdE-yvdF-mdxE-mdxF-mdxG-yvdJ-yvdK-malL-pgcM PubMed

• Expression browser: malL PubMed

• Sigma factor:

• Regulation:
  • induced in the presence of maltose PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Stefan Schönert, Sabine Seitz, Holger Krafft, Eva-Anne Feuerbaum, Iris Andernach, Gabriele Witz, Michael K Dahl
Maltose and maltodextrin utilization by Bacillus subtilis.
J Bacteriol: 2006, 188(11);3911-22
[PubMed:16707683] [WorldCat.org] [DOI] (P p)

S Schönert, T Buder, M K Dahl
Properties of maltose-inducible alpha-glucosidase MalL (sucrase-isomaltase-maltase) in Bacillus subtilis: evidence for its contribution to maltodextrin utilization.
Res Microbiol: 1999, 150(3);167-77
[PubMed:10229946] [WorldCat.org] [DOI] (P p)

S Schönert, T Buder, M K Dahl
Identification and enzymatic characterization of the maltose-inducible alpha-glucosidase MalL (sucrase-isomaltase-maltase) of Bacillus subtilis.
J Bacteriol: 1998, 180(9);2574-8
[PubMed:9573215] [WorldCat.org] [DOI] (P p)