YngG

• Description: 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) lyase
  
  

Gene name	yngG
Synonyms
Essential	no
Product	3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) lyase
Function	mother cell metabolism, leucine utilization
Gene expression levels in SubtiExpress: yngG
MW, pI	32 kDa, 5.753
Gene length, protein length	897 bp, 299 aa
Immediate neighbours	yngF, yngHB
Sequences	Protein DNA Advanced_DNA
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

utilization of amino acids, sporulation proteins

This gene is a member of the following regulons

SigE regulon

The gene

Basic information

• Locus tag: BSU18230

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: (S)-3-hydroxy-3-methylglutaryl-CoA = acetyl-CoA + acetoacetate PubMed

• Protein family: HMG-CoA lyase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 1YDO

• UniProt: O34873

• KEGG entry: [3]

• E.C. number: 4.1.3.4

Expression and regulation

• Operon: yngJ-yngI-yngH-yngHB-yngG-yngF-yngE PubMed

• Expression browser: yngG PubMed

• Sigma factor: SigE PubMed

• Regulation:
  • expressed during sporulation in the mother cell (SigE) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: