YkvU

• Description: spore cortex membrane protein, required for germination at high pressure
  
  

Gene name	ykvU
Synonyms
Essential	no
Product	spore cortex membrane protein
Function	germination at high pressure
Gene expression levels in SubtiExpress: ykvU
MW, pI	49 kDa, 9.551
Gene length, protein length	1335 bp, 445 aa
Immediate neighbours	ykvT, stoA
Sequences	Protein DNA Advanced_DNA
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

germination, membrane proteins

This gene is a member of the following regulons

SigE regulon

The gene

Basic information

• Locus tag: BSU13830

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s): SpoVB, YabM, YtgP

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • forespore membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O31686

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: ykvU-stoA PubMed

• Expression browser: ykvU PubMed

• Sigma factor: SigE PubMed

• Regulation:
  • expressed early during sporulation in the mother cell (SigE) PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:
  • 1S131 ( ykvU::tet), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Allison Fay, Jonathan Dworkin
Bacillus subtilis homologs of MviN (MurJ), the putative Escherichia coli lipid II flippase, are not essential for growth.
J Bacteriol: 2009, 191(19);6020-8
[PubMed:19666716] [WorldCat.org] [DOI] (I p)

Pradeep Vasudevan, Jessica McElligott, Christa Attkisson, Michael Betteken, David L Popham
Homologues of the Bacillus subtilis SpoVB protein are involved in cell wall metabolism.
J Bacteriol: 2009, 191(19);6012-9
[PubMed:19648239] [WorldCat.org] [DOI] (I p)

Abram Aertsen, Isabelle Van Opstal, Suzy C Vanmuysen, Elke Y Wuytack, Chris W Michiels
Screening for Bacillus subtilis mutants deficient in pressure induced spore germination: identification of ykvU as a novel germination gene.
FEMS Microbiol Lett: 2005, 243(2);385-91
[PubMed:15686839] [WorldCat.org] [DOI] (P p)

Daisuke Imamura, Kazuo Kobayashi, Junichi Sekiguchi, Naotake Ogasawara, Michio Takeuchi, Tsutomu Sato
spoIVH (ykvV), a requisite cortex formation gene, is expressed in both sporulating compartments of Bacillus subtilis.
J Bacteriol: 2004, 186(16);5450-9
[PubMed:15292147] [WorldCat.org] [DOI] (P p)

Patrick Eichenberger, Shane T Jensen, Erin M Conlon, Christiaan van Ooij, Jessica Silvaggi, José Eduardo González-Pastor, Masaya Fujita, Sigal Ben-Yehuda, Patrick Stragier, Jun S Liu, Richard Losick
The sigmaE regulon and the identification of additional sporulation genes in Bacillus subtilis.
J Mol Biol: 2003, 327(5);945-72
[PubMed:12662922] [WorldCat.org] [DOI] (P p)