ScoB

• Description: probable succinyl CoA:3-oxoacid CoA-transferase (subunit B)
  
  

Gene name	scoB
Synonyms	yxjE
Essential	no
Product	probable succinyl CoA:3-oxoacid CoA-transferase (subunit B)
Function	lipid metabolism
MW, pI	23 kDa, 4.893
Gene length, protein length	648 bp, 216 aa
Immediate neighbours	yxjF, scoA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

utilization of lipids, sporulation proteins

This gene is a member of the following regulons

CcpA regulon, SigE regulon

The gene

Basic information

• Locus tag: BSU38980

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Succinyl-CoA + a 3-oxo acid = succinate + a 3-oxoacyl-CoA (according to Swiss-Prot)

• Protein family: 3-oxoacid CoA-transferase subunit B family (according to Swiss-Prot)

• Paralogous protein(s): YodR

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P42316

• KEGG entry: [3]

• E.C. number: 2.8.3.5

Expression and regulation

• Operon: yxjC-scoA-scoB-yxjF PubMed

• Expression browser: scoB PubMed

• Sigma factor: SigE PubMed

• Regulation:
  • repressed by glucose (CcpA) PubMed
  • expressed early during sporulation in the mother cell (SigE) PubMed
  • expression is reduced in a SigV mutant PubMed

• Regulatory mechanism:
  • CcpA: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed