PbuE

• Description: putative hypoxanthine exporter
  
  

Gene name	pbuE
Synonyms	ydhL
Essential	no
Product	putative hypoxanthine exporter
Function	nucleotide metabolism
MW, pI	41 kDa, 8.884
Gene length, protein length	1164 bp, 388 aa
Immediate neighbours	ydhK, gmuB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

transporters/ other, nucleotide metabolism/ other, membrane proteins

This gene is a member of the following regulons

A-box

The gene

Basic information

• Locus tag: BSU05800

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: Q797E3

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:
  • induced by hypoxanthine and guanine, PurR-independent PubMed
  • induced by adenine (A-box) PubMed

• Regulatory mechanism:
  • A-box: adenine-controlled riboswitch, transcription termination/ antitermination PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: