GalM

• Description: aldose-1-epimerase
  
  

Gene name	galM
Synonyms	yoxA
Essential	no
Product	aldose-1-epimerase (mutarotase)
Function	unknown
MW, pI	37 kDa, 5.602
Gene length, protein length	975 bp, 325 aa
Immediate neighbours	dacC, yoeA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU18360

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Categories containing this gene/protein

utilization of specific carbon sources

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: aldose-1-epimerase (mutarotase) PubMed

• Protein family: peptidase S13 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: secreted (according to Swiss-Prot)

Database entries

• Structure: 3MWX

• UniProt: P39840

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: galM-dacC PubMed

• Sigma factor: SigH PubMed, SigB PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Colette Duez, Astrid Zervosen, Nathalie Teller, Rémy Melkonian, Emmanuel Banzubazé, Fabrice Bouillenne, André Luxen, Jean-Marie Frère
Characterization of the proteins encoded by the Bacillus subtilis yoxA-dacC operon.
FEMS Microbiol Lett: 2009, 300(1);42-7
[PubMed:19758330] [WorldCat.org] [DOI] (I p)

A Petersohn, J Bernhardt, U Gerth, D Höper, T Koburger, U Völker, M Hecker
Identification of sigma(B)-dependent genes in Bacillus subtilis using a promoter consensus-directed search and oligonucleotide hybridization.
J Bacteriol: 1999, 181(18);5718-24
[PubMed:10482513] [WorldCat.org] [DOI] (P p)

L B Pedersen, T Murray, D L Popham, P Setlow
Characterization of dacC, which encodes a new low-molecular-weight penicillin-binding protein in Bacillus subtilis.
J Bacteriol: 1998, 180(18);4967-73
[PubMed:9733705] [WorldCat.org] [DOI] (P p)