CydB

• Description: cytochrome bd ubiquinol oxidase (subunit II), high affinity terminal oxidase
  
  

Gene name	cydB
Synonyms	yxkL
Essential	no
Product	cytochrome bd ubiquinol oxidase (subunit II), high affinity terminal oxidase
Function	respiration
MW, pI	37 kDa, 9.48
Gene length, protein length	1014 bp, 338 aa
Immediate neighbours	cydC, cydA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU38750

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Ubiquinol-8 + O₂ = Ubiquinone-8 + H₂O (according to Swiss-Prot)

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s): contains an iron-sulfur cluster

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P94365

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: cydA-cydB-cydC-cydD PubMed

• Sigma factor:

• Regulation:
  • repressed by glucose (CcpA)
  • induced under anaerobic conditions (Rex) PubMed
  • expressed under anaerobic conditions (ResD) PubMed

• Regulatory mechanism:
  • CcpA: transcription repression
  • Rex: transcription repression PubMed
  • ResD: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: