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Mycoplasmas as minimal organisms

Sebastian R Schmidl, Katrin Gronau, Nico Pietack, Michael Hecker, Dörte Becher, Jörg Stülke
The phosphoproteome of the minimal bacterium Mycoplasma pneumoniae: analysis of the complete known Ser/Thr kinome suggests the existence of novel kinases.
Mol Cell Proteomics: 2010, 9(6);1228-42
[PubMed:20097688] [WorldCat.org] [DOI] (I p)

Sebastian Kühner, Vera van Noort, Matthew J Betts, Alejandra Leo-Macias, Claire Batisse, Michaela Rode, Takuji Yamada, Tobias Maier, Samuel Bader, Pedro Beltran-Alvarez, Daniel Castaño-Diez, Wei-Hua Chen, Damien Devos, Marc Güell, Tomas Norambuena, Ines Racke, Vladimir Rybin, Alexander Schmidt, Eva Yus, Ruedi Aebersold, Richard Herrmann, Bettina Böttcher, Achilleas S Frangakis, Robert B Russell, Luis Serrano, Peer Bork, Anne-Claude Gavin
Proteome organization in a genome-reduced bacterium.
Science: 2009, 326(5957);1235-40
[PubMed:19965468] [WorldCat.org] [DOI] (I p)

Sven Halbedel, Claudine Hames, Jörg Stülke
Regulation of carbon metabolism in the mollicutes and its relation to virulence.
J Mol Microbiol Biotechnol: 2007, 12(1-2);147-54
[PubMed:17183222] [WorldCat.org] [DOI] (P p)


Identification of a minimal gene set

Yusuke Azuma, Motonori Ota
An evaluation of minimal cellular functions to sustain a bacterial cell.
BMC Syst Biol: 2009, 3;111
[PubMed:19943949] [WorldCat.org] [DOI] (I e)


Steps on the way to an artificial organism


Metabolism

Frederik M Meyer, Jan Gerwig, Elke Hammer, Christina Herzberg, Fabian M Commichau, Uwe Völker, Jörg Stülke
Physical interactions between tricarboxylic acid cycle enzymes in Bacillus subtilis: evidence for a metabolon.
Metab Eng: 2011, 13(1);18-27
[PubMed:20933603] [WorldCat.org] [DOI] (I p)

Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley M Deacon, John Wooley, Scott A Lesley, Ian A Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik
Three-dimensional structural view of the central metabolic network of Thermotoga maritima.
Science: 2009, 325(5947);1544-9
[PubMed:19762644] [WorldCat.org] [DOI] (I p)

Bryson D Bennett, Elizabeth H Kimball, Melissa Gao, Robin Osterhout, Stephen J Van Dien, Joshua D Rabinowitz
Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli.
Nat Chem Biol: 2009, 5(8);593-9
[PubMed:19561621] [WorldCat.org] [DOI] (I p)

Wataru Iwasaki, Toshihisa Takagi
Rapid pathway evolution facilitated by horizontal gene transfers across prokaryotic lineages.
PLoS Genet: 2009, 5(3);e1000402
[PubMed:19266023] [WorldCat.org] [DOI] (I p)

Fabian M Commichau, Fabian M Rothe, Christina Herzberg, Eva Wagner, Daniel Hellwig, Martin Lehnik-Habrink, Elke Hammer, Uwe Völker, Jörg Stülke
Novel activities of glycolytic enzymes in Bacillus subtilis: interactions with essential proteins involved in mRNA processing.
Mol Cell Proteomics: 2009, 8(6);1350-60
[PubMed:19193632] [WorldCat.org] [DOI] (I p)

Armen Y Mulkidjanian, Eugene V Koonin, Kira S Makarova, Sergey L Mekhedov, Alexander Sorokin, Yuri I Wolf, Alexis Dufresne, Frédéric Partensky, Henry Burd, Denis Kaznadzey, Robert Haselkorn, Michael Y Galperin
The cyanobacterial genome core and the origin of photosynthesis.
Proc Natl Acad Sci U S A: 2006, 103(35);13126-31
[PubMed:16924101] [WorldCat.org] [DOI] (P p)

M Ribbe, D Gadkari, O Meyer
N2 fixation by Streptomyces thermoautotrophicus involves a molybdenum-dinitrogenase and a manganese-superoxide oxidoreductase that couple N2 reduction to the oxidation of superoxide produced from O2 by a molybdenum-CO dehydrogenase.
J Biol Chem: 1997, 272(42);26627-33
[PubMed:9334244] [WorldCat.org] [DOI] (P p)


Systematics

James A Lake
Evidence for an early prokaryotic endosymbiosis.
Nature: 2009, 460(7258);967-71
[PubMed:19693078] [WorldCat.org] [DOI] (I p)

Fumito Maruyama, Mitsuhiko Kobata, Ken Kurokawa, Keishin Nishida, Atsuo Sakurai, Kazuhiko Nakano, Ryota Nomura, Shigetada Kawabata, Takashi Ooshima, Kenta Nakai, Masahira Hattori, Shigeyuki Hamada, Ichiro Nakagawa
Comparative genomic analyses of Streptococcus mutans provide insights into chromosomal shuffling and species-specific content.
BMC Genomics: 2009, 10;358
[PubMed:19656368] [WorldCat.org] [DOI] (I e)

Antoine Danchin, Gang Fang, Stanislas Noria
The extant core bacterial proteome is an archive of the origin of life.
Proteomics: 2007, 7(6);875-89
[PubMed:17370266] [WorldCat.org] [DOI] (P p)

J Peter Gogarten, Jeffrey P Townsend
Horizontal gene transfer, genome innovation and evolution.
Nat Rev Microbiol: 2005, 3(9);679-87
[PubMed:16138096] [WorldCat.org] [DOI] (P p)