MprF

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  • Description: synthesis of lysylphosphatidylglycerol (L-PG)

Gene name mprF
Synonyms yfiW, yfiX
Essential no
Product lysylphosphatidylglycerol synthase
Function lysylphosphatidylglycerol lipid biosynthesis
MW, pI
Gene length, protein length
Immediate neighbours yfiV, yfiY
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YfiW context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU08425

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]

Additional information

Gene was re-assembled due to sequencing error in original sequence (it encompasses the genes annotated as yfiX and yfiW in SubtiList) PubMed

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Anna-Barbara Hachmann, Esther R Angert, John D Helmann
Genetic analysis of factors affecting susceptibility of Bacillus subtilis to daptomycin.
Antimicrob Agents Chemother: 2009, 53(4);1598-609
[PubMed:19164152] [WorldCat.org] [DOI] (I p)

Letal I Salzberg, John D Helmann
Phenotypic and transcriptomic characterization of Bacillus subtilis mutants with grossly altered membrane composition.
J Bacteriol: 2008, 190(23);7797-807
[PubMed:18820022] [WorldCat.org] [DOI] (I p)