MgsR
-  Description: transcriptional regulator of a subset of the SigB general stress regulon 
 
| Gene name | mgsR | 
| Synonyms | yqgZ | 
| Essential | no | 
| Product | transcriptional regulator | 
| Function | controls a subset of general stress genes | 
| MW, pI | 14 kDa, 9.28 | 
| Gene length, protein length | 378 bp, 126 aa | 
| Immediate neighbours | trnSL-Gln1, yqgY | 
| Gene sequence (+200bp) | Protein sequence | 
| Caution: The sequence for this gene in SubtiList contains errors | |
 Genetic context  
  This image was kindly provided by SubtiList 
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Contents
The gene
Basic information
- Coordinates:
 
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
 
- SubtiList entry: [2]
 
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: exerts a positive or negative effect on the expression of 53 or 18 stress genes, respectively PubMed
 
- Protein family: Arsenate Reductase (ArsC) family, Spx subfamily
 
- Paralogous protein(s): Spx
 
Extended information on the protein
- Kinetic information:
 
- Domains:
 
- Modification:
 
- Cofactor(s):
 
- Effectors of protein activity:
 
- Interactions:
 
- Localization:
 
Database entries
- Structure:
 
- Swiss prot entry:
 
- KEGG entry: [3]
 
- E.C. number:
 
Additional information
Expression and regulation
- Operon:
 
- Regulation: repressed by Casamino Acids PubMed , induced by stress (SigB) PubMed, expressed under stress conditions PubMed
 
- Regulatory mechanism:
 
- Additional information:
 
Biological materials
- Mutant:
 
- Expression vector:
 
- lacZ fusion:
 
- GFP fusion:
 
- two-hybrid system:
 
- Antibody:
 
Labs working on this gene/protein
Your additional remarks
References
- Mäder et al. (2002) Transcriptome and Proteome Analysis of Bacillus subtilis Gene Expression Modulated by Amino Acid Availability. J. Bacteriol 184: 1844288-4295 PubMed
 - Höper et al. (2005) Comprehensive Characterization of the Contribution of Individual SigB-Dependent General Stress Genes to Stress Resistance of Bacillus subtilis. J. Bact. 187: 2810-2826 PubMed
 - Reder et al. (2008) The Spx paralogue MgsR (YqgZ) controls a subregulon within the general stress response of Bacillus subtilis. Mol. Microbiol. 69: 1104-1120. PubMed
 - Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed
 
