iolG

iolG
168

inositol 2-dehydrogenase

Locus
BSU_39700
Molecular weight
38.20 kDa
Isoelectric point
4.86
Protein length
Gene length
Function
myo-inositol catabolism
Product
inositol 2-dehydrogenase
Essential
no
E.C.
1.1.1.18
Synonyms
iolG, idh, iol

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0673 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
4,075,785  4,076,819
The protein
Catalyzed reaction/ biological activity
myo-inositol + NAD+ --> H+ + NADH + scyllo-inosose (according to UniProt)
1D-chiro-inositol + NAD+ --> H+ + NADH + scyllo-inosine (according to UniProt)
Protein family
Gfo/Idh/MocA family (according to UniProt)
NAD+ PubMed
Structure
Paralogous protein(s)
Expression and Regulation
Operons
Description
Regulation
induced by inositol (IolR) PubMed
Regulatory mechanism
IolR: repression, PubMed, in iolR regulon
CcpA: repression, PubMed, in ccpA regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
Open in new tab

iolAiolJ

2025-01-11 21:13:47

ghost

110

4fd092965338ef1511600132442d2247a2693c98

C19E63046F0B412961D2626F72E0308D922D50B2

Biological materials
Mutant
MGNA-B698 (iolG::erm), available at the NBRP B. subtilis, Japan
BKE39700 (iolG::erm  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATTGACAGCCACTCCTTCT,  downstream forward: _UP4_AACTAAAAAACAGAGGAGTG
BKK39700 (iolG::kan  trpC2) available at BGSCPubMed, upstream reverse: _UP1_CATTGACAGCCACTCCTTCT,  downstream forward: _UP4_AACTAAAAAACAGAGGAGTG
Labs working on this gene/protein
Yasutaro Fujita, University of Fukuyama, Japan
[[Ken-ichi Yoshida]], Kobe University, Japan
References
Loading

93C1DF93CAFC5AE726523A91A3BA7470017FF6DC

Page visits: 5245

Time of last update: 2025-01-18 18:44:40

Author of last update: Jstuelk