CdsA

• Description: phosphatidate cytidylyltransferase
  
  

Gene name	cdsA
Synonyms
Essential	yes PubMed
Product	phosphatidate cytidylyltransferase
Function	biosynthesis of phospholipids
Gene expression levels in SubtiExpress: cdsA
Metabolic function and regulation of this protein in SubtiPathways: cdsA
MW, pI	30 kDa, 7.866
Gene length, protein length	807 bp, 269 aa
Immediate neighbours	uppS, ispC
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

biosynthesis of lipids, essential genes, membrane proteins

The gene

Basic information

• Locus tag: BSU16540

Phenotypes of a mutant

essential PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: CTP + phosphatidate = diphosphate + CDP-diacylglycerol (according to Swiss-Prot)

• Protein family: CDS family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane at the septum PubMed

Database entries

• Structure:

• UniProt: O31752

• KEGG entry: [2]

• E.C. number: 2.7.7.41

Expression and regulation

• Operon:

• Expression browser: cdsA PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information: the mRNA is very stable (half-life > 15 min) PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: