HxlA

• Description: 3-hexulose-6-phosphate synthase
  
  

Gene name	hxlA
Synonyms	yckG
Essential	no
Product	3-hexulose-6-phosphate synthase
Function	ribulose monophosphate pathway for formaldehyde fixation
Gene expression levels in SubtiExpress: hxlA
MW, pI	22 kDa, 4.564
Gene length, protein length	630 bp, 210 aa
Immediate neighbours	hxlB, hxlR
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

resistance against oxidative and electrophile stress

This gene is a member of the following regulons

HxlR regulon

The gene

Basic information

• Locus tag: BSU03460

Database entries

• BsubCyc: BSU03460

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: D-arabino-hex-3-ulose 6-phosphate = D-ribulose 5-phosphate + formaldehyde (according to Swiss-Prot)

• Protein family: HPS subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU03460

• Structure:

• UniProt: P42405

• KEGG entry: [3]

• E.C. number: 4.1.2.43

Expression and regulation

• Operon: hxlA-hxlB PubMed

• Expression browser: hxlA PubMed

• Sigma factor:

• Regulation: induction by formaldehyde (HxlR) PubMed

• Regulatory mechanism: transcription activation by HxlR PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: