HxlR

• Description: MarR/DUF24 family transcription activator of the hxlA-hxlB operon
  
  

Gene name	hxlR
Synonyms	yckH
Essential	no
Product	MarR/DUF24 family transcription activator
Function	regulation of the ribulose monophosphate pathway
Gene expression levels in SubtiExpress: hxlR
MW, pI	14 kDa, 6.358
Gene length, protein length	360 bp, 120 aa
Immediate neighbours	hxlA, srfAA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transcription factors and their control, resistance against oxidative and electrophile stress

The HxlR regulon:

• hxlA-hxlB

The gene

Basic information

• Locus tag: BSU03470

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: transcription activation of the ribulose monophosphate pathway for formaldehyde fixation and detoxification

• Protein family: MarR/DUF24 family

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity: formaldehyde stimulates transcription activation by HxlR

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P42406

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: hxlR (according to DBTBS)

• Expression browser: hxlR PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:
  • A ncRNA is predicted between hxlR and srfAA PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: