YaaT

• Description: control of the phosphorelay, required for the achieving a sufficient level of Spo0A-P for sporulation initiation
  
  

Gene name	yaaT
Synonyms
Essential	no
Product	unknown
Function	regulation of sporulation initiation
Gene expression levels in SubtiExpress: yaaT
Interactions involving this protein in SubtInteract: YaaT
MW, pI	31 kDa, 4.838
Gene length, protein length	825 bp, 275 aa
Immediate neighbours	holB, yabA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

phosphorelay, membrane proteins

The gene

Basic information

• Locus tag: BSU00320

Phenotypes of a mutant

• block of sporulation at stage 0 PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • YmcA-YlbF-YaaT, this complex stimulates Spo0A phosphorylation in the phosphorelay PubMed

• Localization:
  • peripheral membrane, as well as to the septum, during sporulation PubMed

Database entries

• Structure:

• UniProt: P37541

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: yaaT PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Valerie J Carabetta, Andrew W Tanner, Todd M Greco, Melissa Defrancesco, Ileana M Cristea, David Dubnau
A complex of YlbF, YmcA and YaaT regulates sporulation, competence and biofilm formation by accelerating the phosphorylation of Spo0A.
Mol Microbiol: 2013, 88(2);283-300
[PubMed:23490197] [WorldCat.org] [DOI] (I p)

Shigeo Hosoya, Kei Asai, Naotake Ogasawara, Michio Takeuchi, Tsutomu Sato
Mutation in yaaT leads to significant inhibition of phosphorelay during sporulation in Bacillus subtilis.
J Bacteriol: 2002, 184(20);5545-53
[PubMed:12270811] [WorldCat.org] [DOI] (P p)