RplA

• Description: ribosomal protein
  
  

Gene name	rplA
Synonyms
Essential	yes PubMed
Product	ribosomal protein L1 (BL1)
Function	translation
Gene expression levels in SubtiExpress: rplA
Interactions involving this protein in SubtInteract: RplA
MW, pI	24 kDa, 9.732
Gene length, protein length	696 bp, 232 aa
Immediate neighbours	rplK, rplJ
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

translation, essential genes, universally conserved proteins

This gene is a member of the following regulons

stringent response

The gene

Basic information

• Locus tag: BSU01030

Phenotypes of a mutant

essential PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ribosomal protein L1P family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • YsxC-RplA PubMed

• Localization:

Database entries

• Structure:

• UniProt: Q06797

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: rplA PubMed

• Sigma factor:

• Regulation:
  • RelA dependent downregulation (Class I) during stringent response PubMed
  • expression transiently increases in the forespore PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system: B. pertussis adenylate cyclase-based bacterial two hybrid system (BACTH), available in Jörg Stülke's lab

• FLAG-tag construct:
  • GP1094 (erm, based on pGP1087), available in Jörg Stülke's lab

• Antibody: