WalR
- Description: two-component response regulator, controls cell wall metabolism
Gene name | walR |
Synonyms | yycF |
Essential | yes PubMed |
Product | two-component response regulator |
Function | control of cell wall metabolism |
MW, pI | 27 kDa, 4.876 |
Gene length, protein length | 705 bp, 235 aa |
Immediate neighbours | walK, trnY-Phe |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU40410
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
Categories containing this gene/protein
cell wall/ other, transcription factors and their control, essential genes, phosphoproteins
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: OmpR family of two-component transcription regulators
- Paralogous protein(s):
Genes controlled by WalR PubMed
- Activation by WalR: cwlO, lytE, ydjM, yocH, ftsA-ftsZ PubMed, tagA-tagB PubMed, tagD-tagE-tagF PubMed
- Repression by WalR: iseA, yjeA
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: phosphorylated by WalK on an Asp residue
- Cofactor(s):
- Effectors of protein activity: phosphorylation likely affects DNA-binding activity
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- UniProt: P37478
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation: expressed during vegetative growth, repressed during stationary phase PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Original Publications