FruR

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• Description: transcription repressor of the fruR-fruK-fruA operon, DeoR family <br/><br/>

Gene name	fruR
Synonyms
Essential	no
Product	transcription repressor
Function	regulation of fructose utilization
Metabolic function and regulation of this protein in SubtiPathways: <br/>Sugar catabolism
MW, pI	27 kDa, 5.684
Gene length, protein length	753 bp, 251 aa
Immediate neighbours	yknZ, fruK
Get the DNA and protein sequences <br/> (Barbe et al., 2009)
Genetic context <br/> <div align="right"> <small>This image was kindly provided by SubtiList</small></div>

<br/><br/><br/><br/><br/><br/>

The gene

Basic information

• Locus tag: BSU14380

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O31713

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: fruR-fruK-fruA (according to DBTBS)

• Sigma factor:

• Regulation:
  • induced in the presence of fructose (FruR) (according to DBTBS)

• Regulatory mechanism:
  • FruR: transcription repression (according to DBTBS)

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

<pubmed>14651647,10627040, </pubmed>