SpoVAD

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• Description: required for spore maturation <br/><br/>

Gene name	spoVAD
Synonyms
Essential	no
Product	unknown
Function	spore maturation
Metabolic function and regulation of this protein in SubtiPathways: <br/>Lys, Thr
MW, pI	35 kDa, 5.243
Gene length, protein length	1014 bp, 338 aa
Immediate neighbours	spoVAE, spoVAC
Get the DNA and protein sequences <br/> (Barbe et al., 2009)
Genetic context <br/> <div align="right"> <small>This image was kindly provided by SubtiList</small></div>

<br/><br/><br/><br/><br/><br/>

The gene

Basic information

• Locus tag: BSU23410

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure: 3LM6

• UniProt: P40869

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: spoVAA-spoVAB-spoVAC-spoVAD-spoVAE-spoVAF-lysA PubMed

• Sigma factor: SigG PubMed

• Regulation:
  • expressed late during sporulation in the forespore (SigG, SpoVT) PubMed

• Regulatory mechanism:
  • SpoVT: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

<pubmed>17573930,3114420,16077113,11751839,15451103,3926949,17158659,6432957,, 7934830 15699190,1903432,8755877</pubmed>