SpoIID

• Description: cell wall hydrolase (lytic transglycosylase), required for complete dissolution of the asymmetric septum
  
  

Gene name	spoIID
Synonyms	spoIIC
Essential	no
Product	lytic transglycosylase
Function	dissolution of the septal cell wall
MW, pI	37 kDa, 9.764
Gene length, protein length	1029 bp, 343 aa
Immediate neighbours	ywmC, murAA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU36750

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: degrades the glycan strands of the peptidoglycan into disaccharide units PubMed, enhances SpoIIP activity PubMed

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: SpoIID-SpoIIP PubMed

• Localization: cell membrane PubMed

Database entries

• Structure:

• UniProt: P07372

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: spoIID PubMed

• Sigma factor: SigE PubMed

• Regulation:
  • expressed early during sporulation in the mother cell (SigE, SpoIIID) PubMed

• Regulatory mechanism:
  • SpoIIID: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: