Difference between revisions of "FabI"
Line 93: | Line 93: | ||
* '''Regulation:''' | * '''Regulation:''' | ||
+ | ** repressed unless the cells experience a lack of malonyl-CoA ([[FapR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12737802 PubMed] | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
+ | ** [[FapR]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/12737802 PubMed] | ||
* '''Additional information:''' | * '''Additional information:''' |
Revision as of 16:36, 11 June 2009
- Description: enoyl-acyl carrier protein reductase
Gene name | fabI |
Synonyms | yjbW |
Essential | no |
Product | enoyl-acyl carrier protein reductase |
Function | fatty acid biosynthesis |
MW, pI | 27 kDa, 5.605 |
Gene length, protein length | 774 bp, 258 aa |
Immediate neighbours | yjbV, cotO |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Locus tag: BSU11720
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Acyl-[acyl-carrier-protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier-protein] + NADH (according to Swiss-Prot)
- Protein family: FabI subfamily (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- Swiss prot entry: P54616
- KEGG entry: [3]
- E.C. number: 1.3.1.9
Additional information
Expression and regulation
- Operon:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References